When I was younger I would naturally get annoyed at my oldest sister but now we are all pretty close. Because we are human we occasionally irritate each other but we all know how to talk through things now.
I get along with my brother and grand-parents pretty well. I have not talked to my sister in like 5 years? The last time was at our Great-Grandpas funeral that we saw/spoke to each other otherwise it was 10+ years from then. I also dont talk to my mom really. Maybe once every 6 months or so.