Here's who I have on my subscription list that I never ignore when they upload.
Red Letter Media - They review movies, real ones as well as shitty B-movies as a joke. I didn't understand the humor the first few times I ran into them but now I've watched everything they've ever made many times over.
PBS Spacetime - some of the most ambitious educational entertainment videos I've seen in terms of the complexity of the subjects and how little they dumb it down.
Pannenkoek - some autist going to outrageous lengths to try to beat Super Mario 64 without pressing the A button.
Mr. Btongue - reviews games, movies, shows, etc. Occasional SJW shit but I'm always interested in what he has to say.
Historia Civilis - short narratives of ancient battles and events.
3Blue1Brown - videos of random interesting math. Extremely good animated visualizations of things.
Primitive Technology - everyone knows this guy, right? Makes short videos showing himself building primitive tools and shelter without any words and with 0 wasted time.
Veritasium - Science infotainment
Lindybeige - British guy briefly rambles about shit, usually history. Quality depends on whether he has an interesting point to make.or not.
ChipCheezumLPs - the term "Let's Play" has been associated with a lot of complete morons who put no effort into their content or appeal to children. These guys are the professionals. I watch them play games like Uncharted or No More Heroes that I don't have the console for.
Every Frame A Painting - This guy is pretentious, but some of his content is extremely good. Videos about how filmmakers do certain things.